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当前位置:首页 > 产品中心 > 胎牛血清培养基细胞因子 > peprotech细胞因子 > 100-21CPerotech Recombinant Human TGF-β1 (CHO cell derived)CHO细胞衍生TGF-β1

产品名称:Perotech Recombinant Human TGF-β1 (CHO cell derived)CHO细胞衍生TGF-β1

产品型号:100-21C

产品报价:

产品特点:Recombinant Human TGF-β1 (CHO cell derived)此产品规格2ug 10ug 100ug 1mg现货及详细产品信息请!

100-21CPerotech Recombinant Human TGF-β1 (CHO cell derived)CHO细胞衍生TGF-β1的详细资料:

 

Recombinant Human TGF-β1 (CHO cell derived)

Catalog Number:
100-21C
Synonyms:
Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
Description:
The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conional changes by proteins such as thrombospondin-1. TGF-β1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transion of fibroblasts and recently it has been implicated in the ion of skin tumors. Recombinant human TGF-β1 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
AA Sequence:
ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Source:
CHO cells
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 was determined by TGF-β1’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg
 
 
 
 
Cross Reactivity:
Chicken, Cow, Dog, Frog, Monkey, Mouse, Pig, Rabbit, Rat, Human, Mink, Donkey, N/A
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Apoptosis Apoptosis
Cancer Cancer Immune System Immune System
Inflammation Inflammation Proliferation Proliferation
Stem Cells & Differentiation Stem Cells & Differentiation TGF-β Superfamily TGF-β Superfamily
Wound Healing Wound Healing Allergy Allergy
 
 
Country of Origin:
USA
 
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